Publications (129)
ARTICLE
Evaluation in vitro de l’activité antiproliférative d’une crème à base de beurre de karité et de miel destinée à la prise en charge des plaies cancéreuses
Luc Zongo, Bagora Bayala, Charles Bavouma Sombié , Safiatou Traoré, Jacques Simporé, Rasmané Semdé
Certains types de cancer provoquent des plaies cancéreuses (PCs), créant inéluctablement un inconfort pour les malades et leurs soignants ; d’où la nécessité de la recherche de solutions endogènes pour leur traitement dans nos contrées. En effet, le miel, en plus de ses propriétés pharmacologiques connues, possède une cytotoxicité sélective ca(...)
beurre de karité – miel - activité antiproliférative - plaies cancéreuses
ARTICLE
Assessment of pharmacy professionals’ knowledge and practice on the management and dispensing of investigational drugs in clinical trials
Grissoum Tarnagda, Moussa Ouedraogo, Bavouma Charles Sombié, Luc Kouka Delma , Eric Nagaonle Some, Jean Claude Romaric Pingwendé Ouédraogo, Olivier Sombié , Maxime K. Drabo and Rasmané Semdé
In quality approach for the development of clinical research in Africa, the level of knowledge and practices of professionals influences the quality of the trial, the confidence of the sponsors in the performance of sites. We evaluated the management and dispensing of experimental drugs in Burkina Faso. From January to June 2018, we conducted(...)
Pharmacy professional
ARTICLE
Evaluation of the physicochemical quality and antimicrobial performance of amoxicillin and amoxicillin + clavulanic acid discs used in Burkina Faso
Djibril Diallo, B. Gérard Josias Yaméogo, Ouéogo Nikiema, Mohamed Belem, W. Bertrand Goumbri, Belinda Mon´e Bassavé, Abdoul-Salam Ouédraogo, Elie Kabré, Rasmané Semdé
Antibiotic discs used in medical analysis laboratories are sourced from multiple manufacturers and suppliers and
must meet stringent quality requirements. This study aimed to assess the quality and performance of amoxicillin
and amoxicillin + clavulanic acid discs used in Burkina Faso. An evaluation of the use of antibiotic discs was
initia(...)
Antibiotic discs, Assay, Antimicrobial performance, Amoxicillin
ARTICLE
Subacute Toxicity, Subacute Anti-inflammatory and Anti-arthritic Activities of Combination of Hydroethanolic Extract of Terminalia macroptera and Ximenia americana In-vivo
Mahamadou Ballo, Filkpièrè Léonard Da, Sékou Bah, Rokia Sanogo and Estelle N. H. Youl
The aim of this study was to assess the anti-inflammatory effects of a combination of medicinal plants on two models of inflammation. Subacute toxicity was assessed by daily oral administration of 2000 mg/kg body weight (bw). Subacute inflammation and arthritis were induced using the carrageenan air pouch granuloma model and Complete Freund’s(...)
Terminaliamacroptera, Ximenia americana, Combination, Anti-inflammatory effect, Anti-arthritic effects, Oxidative stress
COMMUNICATION
Innovations galéniques et prise en charge des maladies infectieuses
YAMEOGO B. Gérard Josias
Les innovations galéniques constituent un élément fondamental du développement pharmaceutique.
Quand on évoque le sujet d’innovation galénique aujourd’hui, on pense à la nanotechnologie, une voie innovante pour véhiculer des molécules thérapeutiques vers une cible. En effet, de nombreuses substances actives présentent des caractéristiques phy(...)
Mots clés non renseignés
ARTICLE
Preformulation study for the selection of a suitable polymer for the development of ellagic acid-based solid dispersion using hot-melt extrusion
Isaïe Nyamba, Olivier Jennotte , Charles B. Sombié , Anna Lechanteur , Pierre-Yves Sacre , Abdoulaye Djandé, Rasmané Semdé , Brigitte Evrard
Ellagic acid is one of the most studied polyphenolic compounds due to its numerous promising therapeutic properties. However, this therapeutic potential remains difficult to exploit owing to its low solubility and low permeability, resulting in low oral bioavailability. In order to allow an effective therapeutic application of EA, it is theref(...)
Ellagic acid, Polymers, Solid dispersions, Hot melt extrusion, Solubility
ARTICLE
Antiulcer Effect of Aqueous Ethanolic Extracts of Pseudocedrela kotschyi (Schweinf) Harms (Meliaceae) and Ximenia americana L. (Olacaceae)
Edwige T Delma, Moussa Ouédraogo, Aimé S Ouédraogo, Arsène W Nikiema, Moustapha Abdoulaye Gambo, Norbert Ramde, Estelle NH Youl, Assita Sanou-Lamien, Olga Mélanie Lompo, Pierre I Guissou
Purpose: This study aimed to provide pharmacological evidence of Pseudocedrela kotschyi and Ximenia americana in preventing or healing peptic ulcers claimed by traditional healers in Burkina Faso.
Methods: The trunk bark of Pseudocedrela kotschyi and the roots bark of Ximenia americana (Olacaceae) were macerated in mixed ethanol/ water (80:20(...)
Pseudocedrela kotschyi, Ximenia americana, Aqueous ethanolic extract, antiulcer, Antioxidant
ARTICLE
Synergistic anti-inflammatory and analgesic activity of hydroethanolic extracts of Terminalia macroptera Guill. & Perr. and Ximenia americana L.
Mahamadou Ballo 1,*, Sékou Doumbia2, Daouda Dembelé, Raogo Ouedraogo, Estelle N. H. Youl, Rokia Sanogo, Sékou Bah
Inflammation is the reaction of the immune system to an external or internal aggression of the organism. The symptoms (redness, edema, heat and pain) are secondary to the increase in vascular permeability. The hydroethanolic extract of Terminalia macroptera and Ximenia americana has anti-inflammatory properties in vitro. The aim was to examine(...)
Terminalia macroptera, Ximenia americana, combinaison, Synergistic, Antiinflammatory
COMMUNICATION
Evaluation des produits cosmétiques capillaires et des pratiques de conseils en soins capillaires dans les officines de Ouagadougou.
- H. Hermine G. ZIME-DIAWARA, B. Gérard Josias YAMEOGO, Ivette DABERE, Charles B. SOMBIE, N. Amina OUEDRAOGO, Rasmané SEMDE
4èmes Journées des Sciences de la Santé de l’UFR SDS (JSDS)
Mots clés non renseignés
ARTICLE
Evaluation des besoins en préparations hospitalières pédiatriques dans les Centres Hospitaliers Universitaires de Ouagadougou, Burkina Faso
Zimé Diawara Hermine, Sombié B. Charles, Yaméogo B.G. Josias, Bagaya Harouna, Delma Kouka Luc, Semdé Rasmané
Les préparations hospitalières, médicaments préparés au sein des hôpitaux, sont demandées principalement dans les spécialités pédiatrie et dermatologie. Il est rapporté par l’OMS, au sujet des médicaments, le problème de non disponibilité de formes galéniques pédiatriques pourtant utiles pour certains médicaments occasionnant ainsi des adminis(...)
Préparation hospitalière, pharmacie hospitalière, pédiatrie, centre hospitalier universitaire, médicaments
ARTICLE
Development of a chemical tracer and a chromatographic fingerprint for the quality control of finished products based on hydroethanol extract of fresh leaves of Cassia alata (L.) Roxb (Fabaceae.)
Rodolphe P. F. Yaméogo , Salfo Ouédraogo, Boubacar Yaro, Abdoul Karim Sakira , Bavouma C. Sombié , Josias G. B. Yaméogo , Rasmané Semdé
Cassia alata is used in the treatment of dermatoses. Quality control of herbal products remains difficult and complex. This study aims to develop a quality control approach for a hydroethanol extract of fresh Cassia alata leaves (EHCA), raw material and its antimicrobial soap, the finished product.
The chromatographic fingerprint, phytochemic(...)
Cassia alata; quality control; extract; soap.
COMMUNICATION
Microcapsules of Cimbopogon schoenantus essential oil as antimicrobial preservatives for oral delivery forms
Y. B. Gérard Josias, K. Anne Marie, Z. D. Hermine, S. B. Charles, R. Emilie and S. Rasmané
4ème conférence Européenne des Sciences Pharmaceutiques (4th European Conference on Pharmaceutics)
Mots clés non renseignés
ARTICLE
Physicochemical Quality and In Vitro Bioequivalence of Amoxicillin Capsules Marketed in Burkina Faso, Africa
B. Gérard Josias Yaméogo , Wendpouiré Zoungrana-Somé , B. Charles Sombié , Hermine Zimé-Diawara , Bertrand Goumbri, Aïssata Sanfo-Diasso , Elie Kabré , and Rasmané Semdé
Amoxicillin is a penicillin antibiotic widely prescribed to treat many infections. Several brands of oral forms of amoxicillin are available on the local market. The aim of this study was to evaluate the physicochemical quality and in vitro bioequivalence of several brands of amoxicillin capsules (500 mg) marketed in Burkina Faso. Nine differe(...)
amoxicillin, capsules, physicochemical quality, dissolution
ARTICLE
In vitro inhibition of cyclooxygenases, anti-denaturation and antioxidant activities of Malian medicinal plants
Mahamadou BALLO1,3*, Karim TRAORE2,3, Abdoulaye D.A. GUINDO, Seidina A.S DIAKITE, Blaise DACKOUO, Raogo OUEDRAOGO, Sékou BAH, Mahamadou DIAKITE, Rokia SANOGO and Estelle N. H. YOUL
Cyclooxygenase 2 (COX-2) is involved in the production of prostaglandins that sustain the inflammatory process. Inflammatory cells release a number of reactive species. Furthermore, reactive oxygen species can initiate intracellular signaling cascades and enhance the expression of pro- inflammatory genes. The objective was to study the cycloox(...)
X. americana, T. macroptera, Cyclooxygenase, Antioxidant, Protein denaturation
ARTICLE
Use of supercritical CO2 for the sterilization of liposomes: Study of the influence of sterilization conditions on the chemical and physical stability of phospholipids and liposomes
Kouka Luc Delma, Noémie Penoy, Abdoul Karim Sakira, Sabrina Egrek, Rosalie Sacheli, Bruno Grignard, Marie-Pierre Hayette, Touridomon Issa Somé, Brigitte Evrard, Rasmané Semdé, Géraldine Piel
The effects of four potential supercritical carbon dioxide (ScCO2) sterilization conditions on the chemical stability
of 9 phospholipids and on the physicochemical characteristics of liposomes consisting of stable phospholipids,
as well as their sterilization efficiency were evaluated. These conditions were : C1 (ScCO2/70 ◦C/150
bar/240 min(...)
Phospholipids, Liposomes, Supercritical carbon dioxide, Sterilization, Stability, Sterilizing efficacy