Publications (87)
ARTICLE
Genetic Factors Associated with Response to Breast Cancer Chemotherapy in Burkina Faso: Case of the CHEK2 1100delC Mutation
[Fabienne Marie Soudre, Alice Kiba, Raoul Karfo, Arnaud Kouraogo, Mousso Savadogo, Lassina Traore, Aboubacar Bambara, Roland Some, Arsene Kagambega, Damien Konkobo, Florencia Djigma, Elie Kabre, Jacques Simpore and Jean Sakande
Background and Objective: Breast cancer is a major public health burden worldwide. During chemotherapy treatment, the development of therapeutic resistance considerably compromises patientsʼ prognosis. The aim of this study was to investigate the genetic factors associated with response to breast cancer treatment in patients in Burkina Faso, i(...)
CHEK2 1100delC, breast cancer, chemotherapy, chemoresistance, mutation
ARTICLE
Establishment of reference values for prothrombin time, activated partial thromboplastin time and fibrinogen in adults in Burkina Faso
Koumpingnin Nebie, Salam Sawadogo, Catherine Traore, Jerome Koulidiati, Donatien Kima, Florence Alida Wendyam Ouedraogo, Myriam Wendkuni Nikiema/ Minoungou, Salifo Sawadogo, Awa Oumar Toure, Eleonore Kafando
Background: The ordering of clinical haemostasis tests is increasing in Burkina Faso due to the newly emergence of cardiovascular and metabolic diseases. However, appropriate local reference values (RV) are
lacking. Our study aimed to establish RV for prothrombin time (PT), activated partial thromboplastin time (aPTT) and fibrinogen assays. M(...)
haemostasis, reference values, PT, aPTT, fibrinogen
ARTICLE
Association of HLA-DRB1*11 and HLA-DRB1*12 gene polymorphism with COVID-19 in Burkina Faso
Alfred Rakissida Ouedraogo1 , Lassina Traoré2,3, Abdoul Karim Ouattara2,3, Alexis Rakiswende Ouedraogo1 , Sidnooma Véronique Zongo2 , Mousso Savadogo2 , Tatiana Doriane Lallogo2 , Herman Karim Sombie4 , Pegdwendé Abel Sorgho2,4, Teega-wendé Clarisse Ouedraogo2 , Florencia Wendkuuni Djigma2*, Assita Sanou Lamien1 , Albert Théophane Yonli4 , Olga Mélanie Lompo1 and Jacques Simporé2,4
Background The clinical manifestations of coronavirus disease (COVID-19) can vary widely, ranging from
asymptomatic to severe, and may be influenced by the host genetic background. The aim of the present study was
to determine the frequencies of HLA-DRB1*11 and HLA-DRB1*12 allele polymorphisms and their associations with
COVID-19.
Metho(...)
Severe COVID-19, HLA-DRB1*11, HLA-DRB1*12, Genotypes, Burkina Faso
ARTICLE
A Case of Cerebral Aspergillosis in a Patient with Chronic Lymphoid Leukemia
Aimé Sosthène Ouédraogo1,2, Franck Auguste Hermann Adémayali Ido2,3, Ibrahim Savadogo4, Souleymane Ouattara3, Rakiswendé Alexis Ouédraogo2,5, Assita Lamien Sanou2,6, Olga Mélanie Lompo2,6
Cerebral aspergillosis commonly affects immunocompromised hosts, primarily patients on immunosuppressive therapy and those with acquired or immunodeficient states such as AIDS. We report a case of cerebral aspergillosis in a 39-year-old woman with a history of treated chronic lymphocytic leukemia (CLL). Multiple fragments of fixed tissues with(...)
Cerebral Aspergillosis, CLL, Grocott Gomori, Immunohistochemistry
ARTICLE
Pneumatosis Cystoides Intestinalis Revealed by an Occlusive Syndrome: A Case Report
IDO Franck Auguste Hermann Adémayali, OUEDRAOGO Aimé Sosthène, SAVADOGO Ibrahim, OUEDRAOGO Rakiswendé Alexis , OUATTARA Souleymane, LAMIEN-SANOU Assita, LOMPO Olga Mélanie
Introduction: Pneumatosis cystoides intestinalis is a rare condition characterized by the presence of gas cysts in the intestinal wall. It can affect different segments of the digestive tract. Male patients over 50 years old seem to be
more affected. Classically, one opposes the primary or idiopathic forms and the secondary forms. Case Report(...)
Cysts, Gas, Intestinal, Pathology
ARTICLE
Knowledge, attitudes, and practices of healthcare workers regarding human immunodeficiency virus index testing in 2021, Burkina Faso
SMAÏLA OUÉDRAOGO, AHMED KABORE, ISMAËL DIALLO, MAURICE SARIGDA, DÉSIRÉ LUCIEN DAHOUROU, KUILGA BENJAMIN KABRE, ISSA ROMBA, BAPOUGOUNI PHILIPPE CHRISTIAN YONLI, TER TIERO ELIAS DAH and NICOLAS MEDA
Although knowing one's HIV status is a necessary
step in initiating antiretroviral treatment, more than a quarter
of Burkinabe who are HIV-positive do not know their status.
To reach the target of screening at least 95% of people living
with HIV (PLHIV), the country has opted for HIV index
testing (screening of sexual partners, children a(...)
knowledge, attitudes, practices, HIV index testing, Burkina Faso
ARTICLE
The use of Ficus capensis Thunb (Moraceae) in African traditional medicine against female infertility and hypogalactia: literature review
OUEDRAOGO Rakiswendé Alexis1*, OUEDRAOGO Rakissida Alfred1 , Tindano Basile2 , BAYALA Balé2 , SANOU/LAMIEN Assita1
Treatment of infertility and promotion of exclusive breastfeeding are important components of strategies to promote progress in reproductive health. Given the difficulties in accessing medically assisted reproductive techniques and commercial dairy products, African populations sometimes rely on medicinal plants. Ficuscapensis is a fig tree us(...)
Ficus capensis, female infertility, breastfeeding, hypogalactia, African traditional medicine
ARTICLE
Genomic and phenotypic diagnosis of bacterial meningitis in 25 health districts in Burkina Faso between January 2016 and December 2019
Issa Tonde, Juliette Tranchot-Diallo, Dinanibe Kambiré, Absatou Ky-Ba, Mahamoudou Sanou, Idrissa Sanou, Rasmata Ouedraogo-Traoré
This study shows a decrease in the positivity rate for meningitis in
Burkina Faso, with pneumococcus taking the lead among the bacteria responsible, with predominance of serotype 1, which is nonetheless included in the PCV13® vaccine. There were no reports of meningococcal A, highlighting the success of the vaccination campaign with the MenAf(...)
Nm: Neisseria meningitdis; Spn: Streptococcus pneumoniae; Hi: Haemophilus influenzae.
ARTICLE
Évaluation des attitudes et pratiques sur l’élimination des médicaments non utilisés ou périmés par les ménages de la commune de Ouagadougou
Dori Daniel, Guembre Adama, Meda Nicolas, Semde Rasmané
Introduction
L'ensemble des médicaments qui passe entre les mains des consommateurs n'est pas utilisé et certains arrivent souvent à expiration dans les ménages. Ces produits de santé peuvent être sources de risques accidentels et de pollution lorsqu'ils sont insuffisamment éliminés. Au Burkina Faso, il n'existe pas encore de directives d’éli(...)
Mots clés non renseignés
ARTICLE
Facteurs Associés à la Récurrence des Épidémies de Choléra au Niger entre 2011 et 2020
Mahamadou Yacouba Moustapha, Ibrahim Alkassoum, Yanogo. Pauline, Jean Kaboré, Meda. Nicolas
Introduction. Le choléra constitue une urgence majeure de santé publique. En 2017 dans le monde, il a été enregistré 71 foyers d’épidémies de choléra. À ce jour, l'Afrique est la région la plus touchée au monde. Au Niger, les épidémies de choléra surviennent depuis 1970 sous mode épidémique ou endémo épidémique. Cette étude vise donc à contrib(...)
Facteurs, Récurrence, épidémies, choléra, Niger
ARTICLE
A Non-Coding Fc Gamma Receptor Cis-Regulatory Variant within the 1q23 Gene Cluster Is Associated with Plasmodium falciparum Infection in Children Residing in Burkina Faso
Jules Cretin, Mathieu Adjemout, Christelle Dieppois, Frederic Gallardo, Magali Torres, Zachary Merard, Serge Aimé Sawadogo, Christophe Picard , Pascal Rihet, Pascale Paul
Antibodies play a crucial role in activating protective immunity against malaria by interacting with Fc-gamma receptors (FcγRs). Genetic variations in genes encoding FcγRs can affect immune cell responses to the parasite. In this study, our aim was to investigate whether non-coding variants that regulate FcγR expression could influence the pre(...)
Burkina Faso, FCGR, expression quantitative trait loci (eQTL), FCGR2A gene polymorphism, FCGR2B gene polymorphism, Fc-gamma receptor (FCGR) gene polymorphism, Fc-gamma receptors/FcγRs, Plasmodium falciparum parasitemia, malaria, regulatory variants
ARTICLE
Facteurs associés aux comportements sexuels à risque d'infections sexuellement transmissibles chez les élèves à Ouagadougou au Burkina Faso
Smaïla Ouédraogo , Maurice Sarigda , Michel Tawa KI , Charlemagne Ouédraogo , Nicolas Méda
Introduction
La non-satisfaction ou la recherche de satisfaction des besoins psycho-sociaux propres à l'adolescence conduit certains d'entre eux à adopter des comportements parfois dangereux pour leur santé. Ces comportements se traduisent généralement par des expériences sexuelles précoces, la consommation de substances psychoactives, l'imit(...)
Mots clés non renseignés
ARTICLE
Sex-Specific Prevalence of Metabolic Abnormalities by Trend of Urbanization and Age, Among Adults in Burkina Faso: Analysis Using the National Baseline Data
eoffray Diendere, Ahmed Kabore, Jean Kabore, Hermann Lanou, Habib Rasfat Fofana, Boyo Constant Pare, Augustin Nawidimbasba Zeba, Nicolas Meda
lntroduction: Metabolic abnormalities increase with the epidemiological transition in Sub-Saharan African area.
Objective: To report the sex-specific prevalence of metabolic abnormalities in Burkinabè adults by the trend of urbanization
and age, using the national baseline data. Methods: Data of 4365 male/female participants to the 2013 Burk(...)
Sex-Specific Prevalence, Metabolic Syndrome Components, Abnormalities, Urbanization Trend, Age
ARTICLE
Application des Mesures de Radioprotection des Travailleurs dans le Service de Médecine Nucléaire du Centre Hospitalier Universitaire Yalgado Ouédraogo, Burkina Faso
Ouattara Tiémégna Florence, Sanon Hugues, Ouédraogo Sandrine, Gansonré Victor, Tapsoba Théophile Lincoln
Introduction. Le service de médecine nucléaire du Centre Hospitalier Universitaire Yalgado Ouédraogo (CHUYO) est fonctionnel depuis janvier 2012. Après dix années de fonctionnement, nous nous sommes proposés d’évaluer la mise en œuvre des mesures de radioprotection des travailleurs. Matériels et méthodes. Il s’est agi d’une étude transversale(...)
Radioprotection- Travailleurs- Médecine nucléaire- CHUYO
ARTICLE
Facteurs pronostiques et survie des leucémies aiguës de l’adulte au Burkina Faso
Traoré Catherine, Nebié Koumpingnin, Sawadogo Salam, Sanou Adjaratou Fabienne, Héma Arsene, Kafando Eléonore
RÉSUMÉ Introduction/justification. Les leucémies aiguës constituent une urgence à la fois diagnostique et thérapeutique. Notre étude a pour but de décrire les facteurs pronostiques et la survie des adultes atteints de leucémies aiguës au Burkina Faso.
Patients et méthodes. Étude transversale, descriptive à collecte de données rétrospective co(...)
Pronostic, Leucémie aiguë, Adulte, Burkina Faso, Afrique subsaharienne