Abstract. Background: The ordering of clinical haemostasis tests is increasing in Burkina Faso due to the newly emergence of cardiovascular and
metabolic diseases. However, appropriate local reference values (RV) are
lacking. Our study aimed to establish RV for prothrombin time (PT), activated partial thromboplastin time (aPTT) and fibrinogen assays. Methods:
In 2020, we carried out a cross-sectional study at the transfusion centre of
Ouagadougou and included 280 healthy blood donors (140 males and 140
females) as reference subjects (RS) according to CLSI guidelines (C28 A3).
From each RS a 5 mL blood sample had been withdrawn in citrated tubes.
We performed PT, aPTT and fibrinogen assays using the Sysmex™ CA660
coagulometer and Siemens™ reagents. RV were calculated using the “central 95 percentile” method. Results: Reference values of PT, aPTT and
Fibrinogen were respectively [73.84%-117.50%], [20.01-29.45] seconds and
[2.04-3.83] g/L for females and [58.81%-112,31%], [20.9-29.98] seconds and
[1.58-3.35] g/L for males. Conclusion: We report for the first time locally
appropriate haemostasis RV for the Burkina Faso adult’s population. They
will be of clinical use to our health care professionals.

haemostasis, reference values, PT, aPTT, fibrinogen