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Anti-Inflammatory and Anti-Colon Cancer Activities of Mung Bean Grown in Burkina Faso,
Auteur(s): Wendmintiri Jeanne d’Arc Kabré, Durand Dah-Nouvlessounon, Fatoumata/Ba Hama, N. Arnaud Kohonou, Haziz Sina, Maximin Senou, Lamine Baba-Moussa, Aly Savadogo
Auteur(s) tagués: SAVADOGO Aly
Renseignée par : SAVADOGO Aly
Résumé

Widely used in traditional medicine in Asia and recently introduced in Burkina Faso under the name Beng-tigr´e, mung bean is a legume consumed throughout the world and more so in India. The objective of this study was to evaluate the cytotoxicity of the mung bean grown and consumed in Burkina Faso and to study its biological properties such as anti-inflammatory and anticanceractivity of the natural and sprouted seeds. The cytotoxicity of the extracts was tested on Artemia salina larvae, and the antiinflammatory activity was evaluated in vitro by albumin denaturation method using diclofenac as reference molecule. The anticancer activity of hydro-ethanol extracts was evaluated on rats made cancerous with 1,2-dimethylhydrazine (DMH) using 5-fluorouracil as reference molecule. The results showed that the highest yield of the plant extraction was observed with the hydroethanol solvent, both for the natural form of mung bean (MBN) and for its sprouted form (MBG). The cytotoxicity test showed no toxicity of the extracts toward shrimp larvae. The ethanolic extract of germinated mung bean seeds gave the highest anti-in-flammatory activity at 95.13 ± 0.22% inhibition with significant difference (p

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