Détails Publication
Paediatric surgical outcomes in sub-Saharan Africa: a multicentre, international, prospective cohort study,
Lien de l'article: doi:10.1136/ bmjgh-2020-004406
Discipline: Médecine clinique
Auteur(s): Principal investigator (PI) and study guarantor: Naomi Wright (King’s College London, UK). Steering committee: Niyi Ade-Ajayi (King’s College Hospital, UK), Emmanuel Ameh (National Hospital, Abuja, Nigeria), Kokila Lakhoo (Oxford University Hospitals, UK), Dan Poenaru (McGill University, Montreal, Canada), Andrew JM Leather (King’s College London, UK). Data analysis: Emily Rose Smith (Baylor University, Texas, USA), Alessandra Bisquera (King’s College London, UK) and PI. Writing committee: Anyanwu Lofty John Chukwuemeka (Aminu Kano Teaching Hospital, Nigeria), Taiwo Akeem Lawal (University College Hospital, Ibadan, Nigeria), Justine Seyi-Olajide (Lagos University Teaching Hospital), Stephen Tabiri (Tamale Teaching Hospital, Ghana), PI, steering committee and data analysis teams. Lead investigators: Aminu Mohammad, Lawal Abdullahi (Aminu Kano Teaching Hospital, Nigeria), Bertille Ki, Albert Wandaogo, Bernadette Béré (Charles De Gaulle Pediatric University Teaching Hospital, Ouagadougou), Luc Malemo, Elisee Bake (HEAL Africa Hospital, Democratic Republic of the Congo), Nwokoro Collins, Aberibigbe M. O. Shonubi (Olabisi Onabanjo University Teaching Hospital, Nigeria), Sharon Cox (Red Cross War Memorial Children’s Hospital, South Africa). Country leads: Anyanwu Lofty John Chukwuemeka (Aminu Kano Teaching Hospital, Nigeria), Sharon Cox (Red Cross War Memorial Children’s Hospital, South Africa), Bip Nandi (Kamuzu Central Hospital, Malawi), Daniel Sidler (Tygerberg Hospital, South Africa). Local investigators: Benin Republique: Houégban Romeo, Gbenou Antoine Seraphin, Eugene Zoumenou (Centre Hospitalier Universitaire de la Mère et de l'Enfant, Cotonou). Burkina Faso: Bernadette Béré, Bandré Emile, Bertille Ki, Tapsoba W. Toussaint, Albert Wandaogo, Kabre Yvette (Charles De Gaulle Pediatric University Teaching Hospital, Ouagadougou). Cote D’ivoire: Rouma Bankole, Manuela Ehua, Agbara Kouame, Moulot Olivier (Teaching Hospital Treichville, Abidjan), Nandiolo Rose (University Hospital De Bouaké). Democratic Republic of the Congo: Jacques Fadhili Bake (HEAL Africa Hospital, Goma). Ethiopia: Mesay Hailemariam Asfaw, Miliard Derbew, Gudeta Didi, Hanna Getachew, Woubedil Kiflu, Samuel Negash, Tihitiena Negussie, Amezene Tadesse, Fiseha Temesgen (Tikur Anbessa Specialized Hospital, Addis Ababa). Ghana: William Appeadu-Mensah, Afua Hesse, Samuel Osei-Nketiah (Korle Bu Teaching Hospital, Accra), Francis Atidana Abantanga, Emmanuel Owusu Abem, Theophilus Teddy Kojo Anyomih, Adakudugu Ida, Osman Imoro, Martin Kyere, Anwar Sadat Seidu, Stephen Tabiri, Paul M. Wondoh (Tamale Teaching Hospital). Kenya: Thomas Kirengo (Embu Level 5 Hospital), Michael Ganey, Michael Mwachiro, Robert K Parker, Sinkeet Ranketi (Tenwek Hospital, Bomet). Malawi: Bitiel Banda, Caroline Melhado, Bip Nandi BMJ Glob Health: first published as 10.1136/bmjgh-2020-004406 on 2 September 2021. Downloaded from http://gh.bmj.com/ on September 3, 2021 by guest. Protected by copyright. 12 PaedSurg Africa Research Collaboration. BMJ Global Health 2021;6:e004406. doi:10.1136/bmjgh-2020-004406 BMJ Global Health (Kamuzu Central Hospital, Lilongwe), Eric Borgstein, Mohakhelha Nyamulani, Emma Thomson, Johannes Verweij (Queen Elizabeth Central Hospital, Blantyre). Niger: Moustapha Helle (Niamey National Hospital). Nigeria: Emmanuel Ameh, Paschal Anyanwu, Matthias Igoche (Abuja National Hospital), Elizabeth Ogboli-Nwasor, Baba Suleiman, Sholadoye Tunde Talib (Ahmadu Bello University Teaching Hospital, Zaria), Mustapha Abdulazeez, Lawal Abdullahi, Farinyaro Aliyu, Aminu Mohammad, Aliyu Mohammed (Aminu Kano Teaching Hospital), Bassey Edem, Terlumun Patrick, Charles Soo (Benue State University Teaching Hospital), Akinlabi Emmanuel Ajao, Olayemi Anthony Ajiboye, Michael Abel Alao (Bowen University Teaching Hospital, Ogbomoso), Odion-obomhense kesiena Helen (Delta state university teaching hospital Ogharra, Delta state), Opeoluwa Adesanya, Adenike Odewabi, Anuoluwapo Aremo (Federal Medical Centre, Abeokuta), Taiwo Jones Olaoluwa, Odi Temitope (Federal Medical Centre, Lokoja), Kayode Bamigbola, Uduehe Enono E. (Federal Medical Centre, Owo, Ondo State), Olalekan Ajai, Omolara Faboya, Abdulsalam Moruf, Roland I Osuoji, Omolara M. Williams (Lagos State University Teaching Hospital), Fatuga Adedeji, Adesoji Ademuyiwa, Felix Alakaloko, Christopher Bode, Ihediwa Chibuike, Ibironke Desalu, Olumide Abiodun Elebute, Charles Ememonu, Oluwaseun Ladipo-Ajayi, Sola Kushimo, Justina Seyi-Olajide, Kayode Olayade, Adebambo Olowu, Justine Seyi-Olajide (Lagos University Teaching Hospital), Okechukwu Hyginus Ekwunife, Victor Ifeanyichukwu Modekwe, Obiechina Sylvester Okwuchukwu, Ngozi Chidinma Osuji, Ezidiegwu Ugochukwu Stanley, Jideofor Okechukwu Ugwu, Chuka Ifeanyichukwu Ugwunne (Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State), Collins Chijioke Adumah, Oludayo Adedapo Sowande, Ademola Olusegun Talabi (Obafemi Awolowo University Teaching Hospital, Ile Ife), Lukmon Amosu, Nwokoro Collins, Ibukunolu Ogundele, Aderibigbe M. O. Shonubi (Olabisi Onabanjo University Teaching Hospital), Felix Kumolalo (Ondo State Trauma and Surgical Centre), Taiwo Akeem Lawal, Olakayode Ogundoyin, Dare Olulana (University College Hospital, Ibadan), John Chinda, Osagie Olabisi, Samson Olori (University of Abuja Teaching Hospital, Gwagwalada), Stella Eguma, Akan Inyang, Ijeoma Esther Nwachukwu (University of Calabar Teaching Hospital), Nurudeen Toyin Abdulraheem, Lukman O. Abdur-Rahman, James O. Adeniran, Muslimat A. Alada, Abdulrasheed A. Nasir, David C. Nwosu (University of Ilorin Teaching Hospital, Ilorin), Christopher C Amah, Sebastian Okwuchukwu Ekenze, Uchechukwu Obiora Ezomike, Emmanuel I. Nwangwu, Ijeoma C. Obianyo, Nene E Obianyo, Nwankwo Elochukwu Perpetua (University of Nigeria Teaching Hospital, Ituku/ Ozalla, Enugu), Alfred T Aggo, Tobin Maxwell, Philemon Okoro (University of Port Harcourt Teaching Hospital). Republic of Cameroon: James A. Brown, Moses Kasumba, Steve Kyota (Mbingo Baptist Hospital). Somaliland: Joy Robinson (Edna Adan Maternity Hospital). South Africa: Seo-Hwa Chung, Savannah smit, Stephanie Van Straten, Andre Theron (Charlotte Maxeke Johannesburg Academic Hospital), Andrew Grieve, Robert Jaich, Jerome Loveland (Chris Hani Baragwanath Hospital), Charles Carapinha (Clinton Hospital, Johannesburg), Milind Chitnis, Mie Elsen, Nayha Gautam (East London Hospital Complex, Walter Sisulu University), Damian Clarke, Shamaman Harilal, Sanele Madziba, Hansraj Mangray, Reitze Rodseth (Grey's Hospital, Pietermaritzburg Metropolitan Hospital Complex), Sharon Cox, Babalwa Nondela, Toru Shimizu (Red Cross War Memorial Children's Hospital), Roel Matos-Puig, Ria Naidoo, Arasha Thotharam (Stranger Hospital, Kwazulu-Natal), Kondjela Sara Hamunyela, Daniel Sidler, Corne De Vos (Tygerberg Hospital, Stellenbosch University). Sudan: Ali Hamad (Gezira National Center of Paediatric Surgery, Wad-Medania), Abdelbasit E Ali, Enas Musa Ismail (Soba University Hospital, Khartoum). Tanzania: Larry Akoko, Robert Bahati, Zaitun M Bokhary, Yona Ringo (Muhimbili National Hospital, Dar es Salaam), Peter Dattani, Ezekiel Kambona, Silas Msangi (Tumbi Regional Referral Hospital, Kibaha). Togo: Komla Gnassingbé, Hamza Doles Sama (Sylvanus Olympio Teaching Hospitalier, Lome). Uganda: Nasser Kakembo, Phyllis Kisa, Mary T Nabukenya, John Sekabira (Mulago National Referral Hospital, Kampala). Zambia: Bruce Bvulani, Mulewa Mulenga, Emma Lillie, Rae Oranmore-Brown, Hope Phiri, Victoria Simiyu (University Teaching Hospital (UTH) in Lusaka). Zimbabwe: Tungamirai Gwatirisa, Bothwell Mbuwayesango (Harare Central Hospital).
Auteur(s) tagués: KI Kelan Bertille
Renseignée par : KI Kelan Bertille
Résumé

Introduction As childhood mortality from infectious diseases falls across sub-Saharan Africa (SSA), the burden of disease attributed to surgical conditions is increasing. However, limited data exist on paediatric surgical outcomes in SSA. We compared the outcomes of five common paediatric surgical conditions in SSA with published benchmark data from high-income countries (HICs).
Methods A multicentre, international, prospective cohort study was undertaken in hospitals providing paediatric
surgical care across SSA. Data were collected on consecutive children (birth to 16 years), presenting with gastroschisis, anorectal malformation, intussusception, appendicitis or inguinal hernia, over a minimum of 1
month, between October 2016 and April 2017. Participating hospitals completed a survey on their resources available for paediatric surgery. The primary outcome was all-cause in-hospital mortality. Mortality in SSA was compared with published benchmark mortality in HICs using χ2 analysis. Generalised linear mixed models were used to identify patient-level and hospital-level factors affecting mortality. A p

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