Introduction: The main objective of this study was to investigate abnormalities
of serum protein fractions in hemodialysis patients with chronic renal
failure (CRF) in Ouagadougou, Burkina Faso. Methods: This was a descriptive
cross-sectional study of 48 hemodialysis patients with chronic renal failure
(CRF) recruited at the Yalgado Ouedraogo Teaching Hospital (YO-TH),
and 48 controls declared fit to donate blood by the Regional Blood Transfusion
Center (RBTC) of Ouagadougou. Urea, creatinine, uric acid, and serum
proteins were measured on the ARCHITECT C4000 equipment (ABOTT®),
while the separating of the different protein fractions was performed on the
Helena SAS 3 & 4 automated system. Results: A total of 96 individuals were
included in the study. Protein levels were on average higher in controls (75.19
± 6.56 g/L) than in hemodialysis patients (71.44 ± 12.33 g/L). Low blood albumin
was significantly associated with the CRF hemodialysis groups compared
to controls (p

Protein Fractions, Albumin, Globulin, Hemodialysis