Epidermoid cyst is an unusual and very rarely described lesion in the kidney. We report the case of a 45-year-old
woman with no known pathological history who presented with right flank pain accompanied by macroscopic
hematuria. The physical examination was unremarkable. The CT scan evoked a malignant tumor in front of a
right renal mass with irregular contours. The patient underwent a total right nephrectomy. The nephrectomy
specimen received for pathological examination showed macroscopically an encapsulated cystic mass of 4 cm
long axis. The cyst lumen was occupied by solid brownish tissue debris. Histologically, the cystic wall was lined
by a keratinizing squamous epithelium with accumulation of keratin lamellae in the cystic lumen. Anatomopathological
examination concluded to the diagnosis of renal epidermoid cyst.

Epidermoid cyst, Renal, Histopatholgy