Objective We assessed the impact of a digital clinical decision support (CDS) tool in improving health providers adherence to recommended antenatal protocols and service quality in rural primary-level health facilities in Burkina Faso.

Design A quasi-experimental evaluation based on a cross-sectional post-intervention assessment comparing the intervention district to a comparison group.

Setting and participants The study included 331 direct observations and exit interviews of pregnant women seeking antenatal care (ANC) across 48 rural primary-level health facilities in Burkina Faso in 2021.

Intervention Digital CDS tool to improve health providers adherence to recommended antenatal protocols.

Outcome measures We analysed the quality of care on both the supply and demand sides. Quality-of-care service scores were based on actual care provided and expected care according to standards. Pregnant women’s knowledge of counselling and satisfaction score after receiving care were also calculated. Other outcomes included time of clinical encounter.

Results The overall quality of health service provision was comparable across intervention and comparison health facilities (52% vs 51%) despite there being a significantly higher proportion of lower skilled providers in the intervention arm (42.5% vs 17.8%). On average, ANC visits were longer in the intervention area (median 24 min, IQR 18) versus comparison area (median 12 min, IQR: 8). The intervention arm had a significantly higher score difference in women’s knowledge of received counselling (16.4 points, 95% CI 10.37 to 22.49), and women’s satisfaction (16.18 points, 95% CI: 9.95 to 22.40).

Conclusion Digital CDS tools provide a valuable opportunity to achieve substantial improvements of the quality of ANC and broadly maternal and newborn health in settings with high burden mortality and less trained health cadres when adequately implemented.

digital clinical decision support, antenatal care, quasi-experimental evaluation, sanitary district