For the control of multiple new and resurgent diseases associated with microbial resistance to antimicrobials, there is renewed interest in using herbal medicines. However, the efficacy safety issues and good manufacturing practices associated with herbal medicines are major aspects to consider. The presence of pathogenic microorganisms in herbal medicines may adversely affect the therapeutic potential of the product or even make the product harmful to the patient. This study aimed quality and the microbiological hazard of herbal medicine produced and sold in city of Ouagadougou. Thus, a total of 45 samples of herbal medicines were collected randomly from the production sites of traditional practitioners and the various points of sale in Ouagadougou by herbalists. Research and enumeration of the total aerobic mesophilic flora, total coliforms, thermotolerant coliforms, yeasts, and some specific pathogenic bacteria such as Salmonella sp, d according to methods based on standard procedures. Good manufacturing practices were also assessed through sample filtration on a 0.45 μm then a cloth sieve to detect physical contaminants. The results were interpreted according to European Pharmacopoeia standards and microbiological criteria for ready-to-eat meals. was noted the presence of S. aureus CFU/ml). The average loads of the different germs in the traditional medicines of the production and sales sites were respectively 1.26.106 and 4.36.106 CFU/ml for the CFU/ml for yeast and moulds, 0.34.104 and CFU/ml and 4.15.103 CFU/ml for thermo tolerant . The search for physical contaminants revealed presence of sand, leaf pieces, and stems in me traditional medicines. In sum, this study demonstrated the presence of some pathogenic bacteria use oral herbal medicines and lake of good manufacturing practices and hygienic of phytomedicines in health systems throughout the world and particularly in developing countries, it is necessary to train and sensitize producers of phytomedicines in good manufacturing practices and hygiene.

Herbal Medicines, Hygienic Quality, Microbiological Quality