Emerging diseases apparition and micro-organisms’s resistance development have shown the insufficiency of synthetic molecules in pathologies treatment. In Burkina Faso, the resort to many plant recipes become systematical by population for the treatment of numerous pathologies. Cymbopogon giganteus, is one of the plants widely used by the local population. The different organs of this plant are often used alone or in combination with other plants or plant organs in the management of malaria, hypertension, hepatitis, insomnia, yellow fever, etc. (Moussa et al., 2012 and Ouattara-Sourabie et al., 2017). Although the plant is one of most cited species last decades in many traditional anti-malarial recipes in some regions of the country, the first scientific work on non-volatile extracts of C. giganteus from Burkina Faso was our thesis work (Bationo, 2019). During this work, the antiplasmodial and antifungal efficacy of different plant organs extracts was evaluated (Bationo et al., 2017aBationo et al., 2017b). The results showed that methanol extracts of leaves and flowers have, on chloroquine-resistant (K1) and chloroquine-sensitive (3D7) strain, an antiplasmodial activity very similar to quinine [IC50 = 0.17 μg/mL]. The evaluation of antifungal activity showed that the same extracts, at low dose, inhibited to about 23% the radial growth of some foodstuff fungi (Bationo et al., 2017aBationo et al., 2017b). However, the chemical structure of the major compounds was still unknown. This work is a continuation of what has been undertaken and its aims is to isolate and characterize the structure of the main molecules in the extracts of C. giganteus. The aim is to contribute to a better knowledge of Burkina Faso flora through an analysis of bioactive molecules contained in the different organs.

Cymbopogon giganteus Flavonoids HPLC HTLC LC-MS NMR