Objectives: Few studies addressed the efficacy of human insulin regimens (mostly premix insulin) used in many lowand- middle income countries on glycemic control of children and adolescents with diabetes. The aim of this study was to assess the efficacy of the premix insulin on the glycated hemoglobin (HbA1c) in comparison to the regular with NPH insulin scheme.
Methods: A retrospective studywas carried out fromJanuary 2020 to September 2022 on patients with type 1 diabetes aged below 18 years followed in Burkina Life For A Child program. They were categorized into three groups, on regularwith NPH insulin (Group A), on premix insulin (Group B) and on regular with premix insulin (Group C). Outcome was analyzed based on HbA1c level.
Results: Sixty-eight patients with a mean age of 15.38 ± 2.26 years and the sex ratio (M/W) 0.94 were studied. There were 14 in Group A, 20 in Group B, and 34 patients in Group C. The mean HbA1c value in the corresponding insulin regimen was 12.8 ± 1.39%, 9.87 ± 2.18%,and 10.66 ± 2.1%, respectively. Glycemic controlwas better in Groups B and C than Group A (pand 10.66 ± 2.1%, respectively. Glycemic controlwas better in Groups B and C than Group A (p

insulin regimen; NPH insulin; premix insulin; type 1 diabetes.