BACKGROUND: Persistent infection with high-risk (HR) papillomavirus (HPV)
genotypes plays a central role in the pathogenesis of invasive cervical cancer.
OBJECTIVES: This study aimed to determine the prevalence and distribution of
HR-HPV among women with or without cervical lesions at VIA/VILI in Togo.
METHODS: Cervical samples were collected from 238 women with or without cervical
lesions at VIA / VILI and[c3] DNA [c4]was extracted and analyzed by real-time
multiplex PCR. Logistic regression analysis was used to determined risk factors
associated with HPV infection.inPietro Annigoni Biomolecular Research Center
(CERBA / LABIOGENE) in Burkina Faso.
RESULTS: The age of the women ranged from 17 to 61 years old, and most were
married (73.5%). The prevalence of HRHPV was 35.71% and this was higher in the
age range 35-39 years. The six most common genotypes were HPV 31 (18.7%), HPV 52
(13.82%), HPV 68 (13.01%), HPV 66 (9.76%), HPV 58 (8.13%) and HPV 56 (8.13%).
Genotypes HPV 18 (4.07%) and HPV 16 (0.81%) were less frequent.[c5] Married or
living with a partner was associated with HPV infection (OR=2,17, IC
[1.20-3.91], p

Genotyping; High-risk; Human papillomavirus; Kara; Togo.