Détails Publication
Antioxidative, anti-inflammatory potentials and phytochemical profile of Commiphora africana (A. Rich) Engl. (Burseraceae) and Loeseneriella africana (WILLD) (Cel...,
Lien de l'article: Article
Discipline: Sciences biologiques
Auteur(s): Moussa Compaoré, Roland Nâg-Tiéro Meda; Sahabi Bakasso; Laurian Vlase, Martin Kiendrebeogo
Auteur(s) tagués: COMPAORE Moussa
Renseignée par : COMPAORE Moussa
Résumé

Objective To assess the antioxidant and anti-inflammatory activities as well as to determine the flavonoids and phenolic acids content of active fractions. Methods Two medicinal plant samples were extracted successively in Soxhlet apparatus with n-hexane, dichloromethane, acetonitrile, ethyl acetate, methanol and n-butanol. Five methods were used to evaluate the antioxidant activity. Anti-inflammatory activity was done through the inhibition of the cyclooxygenase enzymes (COX-1 and COX-2). Polyphenolic compounds were analyzed by using a spectrophotometrical and high performance liquid chromatography-mass spectrometry (HPLC-MS) methods. Results The data showed that the stem leaves extracts of Commiphora africana and Loeseneriella africana possessed significant in vitro antioxidant and anti-inflammatory activities. Polar extracts had radical scavenging effects and they …

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