Détails Publication
Angeli's Salt (Na2N2O3) is a Precursor of HNO and NO: a Voltammetric Study of the Reactive Intermediates Released by Angeli's Salt Decomposition,
Lien de l'article:
Auteur(s): I. TAPSOBA
Auteur(s) tagués: TAPSOBA Issa
Renseignée par : TAPSOBA Issa
Résumé

Under physiological conditions, it is usually accepted that the aerobic decomposition of Angeli's salt produces nitrite (NO2−) and nitroxyl (HNO), which dimerizes and leads to N2O. No consensus has yet been established on the formation of nitric oxide (NO) and/or peroxynitrite (ONOO−) by Angeli's salt. Because this salt has recently been shown to have pharmacological properties for the treatment of cardiovascular diseases, identification of its follow‐up reactive intermediates is of increasing importance. In this work, we investigated the decomposition mechanism of Angeli's salt by voltammetry performed at platinized carbon fiber microelectrodes. By following the decomposition process of Angeli's salt, we showed that the mechanism depends on the experimental conditions. Under aerobic neutral and slightly alkaline conditions, the formation of HNO, NO2−, but also of nitric oxide NO …

Mots-clés

939
Enseignants
5607
Publications
49
Laboratoires
84
Projets