Inhibitory Activity of Methanolic Extracts of Six (06) Medicinal Plants on the Growth ofEscherichia coli Resistant to Imipenem by Production of Carbapenemase Isolated at the Tengandogo Hospital in Ouagadougou
- Journal of Biosciences and Medicines , 13 (5) : 185-196
Résumé
The fight against bacterial infections is essentially based on the use of antibiotics. Unfortunately, bacteria have developed resistance mechanisms against
antibiotics, particularly those of the β-lactam family. Thus, this study aims to evaluate the inhibitory activity of six medicinal plants resulting from an ethnobotanical investigation of these formidable bacteria. Plant methanol extracts were obtained using Soxhlet. The photometric method was used to measure the absorbances of bacterial (Escherichia coli) suspensions and for the phytochemical assay of plant extracts. Terminalia laxiflora (T. laxiflora) Engl. & Diels proves to be the most effective plant with an optical density (OD) of 0.322 against 1.133 of the positive control and 0.901 of the antibiotic.
Mots-clés
Medicinal Plants, Escherichia coli, Carbapenemase, Tengandogo Hospital