Acceptabilité d'un essai vaccinal contre le VIH à moyen terme au Burkina Faso : perceptions des acteurs

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Résumé

INTRODUCTION: The ideal response to HIV would be the discovery of an effective vaccine. Evaluation of the benefit/risk balance of this vaccine must include Africa, where the majority of HIV infections are observed. This study was designed to identify the perceptions and the medium-term acceptability of a potential vaccine trial in Ouagadougou (Burkina Faso). METHODS: After a "literature review", data were collected from key informants, "pimps" of prostitutes, representatives of HIV and/or AIDS associations, facilitators and peer educators. Data were transcribed and analysed manually. RESULTS: The vast majority of respondents considered that it would be relevant to test an HIV vaccine in Ouagadougou (Burkina Faso). Almost all prostitutes would participate in such a trial and would be motivated by several factors. Potential participants were willing to play the role expected of them. A real communication strategy will be needed to conduct this trial. DISCUSSION: The results of this study are similar to those of previous studies conducted in Burkina Faso concerning the acceptability/feasibility of clinical trials. Acceptability studies of clinical trials are therefore becoming less and less relevant. Reinforcing the skills/capacities of all stakeholders and/or adequate preparation of participants to play the role expected of them are therefore now more important than acceptability studies.

Mots-clés

HIV vaccine, clinical trial participation, key informants, sex workers, peer educators, stakeholder perspectives, Ouagadougou, Burkina Faso